Assessment of immunological responses to tumour antigens relevant to the development of therapeutic cancer vaccines
P53 protein that has been referred to as the "guardian of genome". It acts to suppress tumour development through mechanisms involving cell cycle arrest, DNA repair, senescence and apoptosis. Loss of the tumour-suppressive activity in p53 is a frequent event, occurring in more than 50% of...
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Nottingham Trent University
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.686900 |