Age-related epigenetic changes at base excision repair genes and their modulation by dietary restriction in mice

Accumulation of damage in DNA is a characteristic feature of ageing which may result from a decline in DNA repair efficiency. Base excision repair (BER) is the primary mechanism used to repair small-scale DNA damage such as that caused by oxidation. I hypothesised that epigenetic events contribute t...

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Bibliographic Details
Main Author: Górniak, Joanna Paulina
Published: University of Newcastle upon Tyne 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684855