The role of FGF19 in the diagnosis and pathophysiology of primary bile acid diarrhoea

Introduction: PBAD is a common cause of watery diarrhoea. It is diagnosed by the SeHCAT test and is characterized biochemically by elevated bile acid biosynthesis and low fasting FGF19. FGF19 is a gut hormone produced in the terminal ileum which negatively feeds back on hepatic BA synthesis. Aims: T...

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Bibliographic Details
Main Author: Johnston, Ian
Other Authors: Walters, Julian ; Thursz, Mark
Published: Imperial College London 2015
Subjects:
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682084