The Hippo effector TAZ in rhabdomyosarcoma

Persistent hyperactivity of the Hippo effector YAP in activated but not quiescent satellite cells (muscle stem cells) can give rise to embryonal rhabdomyosarcoma (ERMS). Taz is a paralogue of Yap and both have similar functions in most cell types. However, one report has suggested that Taz can, unli...

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Bibliographic Details
Main Author: Mohamed, Abdalla Ahmed Diaai
Published: University of Aberdeen 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680969