Inhibition of treatment-induced cell survival signalling enhances radiosensitivity of PTEN-deficient prostate cancer

Loss of the tumour suppressor PTEN is a common feature of prostate cancer (PCa) and has recently been identified as a prognostic factor for patient relapse following radiotherapy. Published studies in our laboratory have identified CXCL8 signalling as a mediator of PTEN-depleted disease progression...

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Bibliographic Details
Main Author: Armstrong, Chris
Published: Queen's University Belfast 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680869