Host proteolytic and inflammatory responses due to anaerobic infection in cystic fibrosis

Obligate anaerobic bacteria such as Prevotella are present in large numbers in the lower airways of Cystic Fibrosis (CF) patients. However, their contribution to the development and/or perpetuation of bronchiectasis is unknown. In CF, unopposed Matrix Metalloproteinase (MMP) activity drives loss of...

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Bibliographic Details
Main Author: Jackson, Megan
Published: Queen's University Belfast 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.680071

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