Targeting Ras GTPases in murine models of renal fibrosis
End stage kidney disease (ESKD) affects over 5300 people. The progression of chronic kidney disease (CKD) to ESKD is characterised by cytokine stimulation, leading to the activation of myofibroblasts, resulting in fibrosis. Kirsten rat sarcoma (KNRas) has a key role in the proliferation of renal fib...
Main Author: | Newbury, Lucy Jade |
---|---|
Other Authors: | Hendry, Bruce Melville ; Sharpe, Claire Catherine |
Published: |
King's College London (University of London)
2015
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677169 |
Similar Items
-
A study of the effects of Ki-Ras inhibition by antisense deoxyoligonucleotides in a rat model of renal fibrosis
by: Wang, Joe
Published: (2012) -
Renal stones in adults with cystic fibrosis
by: McSorley, Anita D.
Published: (2009) -
Role of microRNAs in renal fibrosis
by: Krupa, Aleksandra
Published: (2010) -
Biomarkers of glomerular inflammation and fibrosis
by: Yu, Mei-Ching
Published: (2014) -
An experimental model of microcystic renal disease
by: McGeoch, J. E. M.
Published: (1973)