Improving the sensitivity and specificity of LC/MS to enable bioanalysis of therapeutic and endogenous proteins and peptides
This thesis establishes LC/MS as a viable, robust, and attractive alternative analytical platform to ligand binding assays for the quantification of therapeutic and endogenous peptides/proteins in biological fluids. A rigorous investigation of the parameters that affect assay sensitivity, specificit...
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King's College London (University of London)
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677134 |