Screening and delineation of molecular mechanisms of action of HbF inducing agents for the treatment of β-thalassaemia
Current agents used for pharmacological reactivation of foetal haemoglobin (HbF) have limited application due to moderate therapeutic properties, variable patient response and potential cytotoxic effects. Therefore, identification of novel HbF inducing agents is still a major research goal to this d...
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King's College London (University of London)
2015
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677113 |