How the therapeutic cancer drug lenalidomide impacts Natural Killer cell immune responses

As multiple myeloma (MM) progresses, Natural Killer (NK) cell responses decline against malignant plasma cells. The immunomodulatory drug lenalidomide is widely used for the treatment of MM but its influence on NK cell biology is unclear. Here, a combination of functional assays and microscopy techn...

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Bibliographic Details
Main Author: Lagrue, Kathryn
Other Authors: Davis, Daniel ; Selkirk, Murray
Published: Imperial College London 2015
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676822