The Abc4⁻/⁻ mouse model of Stargardt disease- : phenotype and therapeutic strategies

Stargardt disease is caused by mutations in the ABCA4 gene and is probably the commonest inherited cause for retinal degeneration in youth with progressive visual deterioration. The Abca4-/- mouse is an animal model mimicking certain aspects of the human disease, including an accumulation of autoflu...

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Bibliographic Details
Main Author: Charbel Issa, Peter
Other Authors: MacLaren, Robert E.
Published: University of Oxford 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669888