Single molecule studies of a voltage-gated potassium channel

This thesis aims to study the activation and deactivation mechanism of voltage-gated K+ channels (Kv), through fluorescence and electrical measurements. Transmembrane voltage changes are detected by the voltage sensor (helices S3b-S4) among Kv, a phenomenon which triggers a conformational change to...

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Bibliographic Details
Main Author: Angué, Lauriane
Other Authors: Tucker, Stephen; Wallace, Mark
Published: University of Oxford 2013
Subjects:
546
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669847

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