Investigating patterns of T cell differentiation in the blood and skin of patients with melanoma
Melanoma progression occurs despite evidence of melanoma-specific T cell activation. Chronic or repeated antigen stimulation can cause dysregulated T cell differentiation through upregulation of inhibitory receptors (immune exhaustion) or end-stage differentiation (immune senescence). This thesis th...
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University College London (University of London)
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.668430 |