Identification of HETE isoforms produced by activated platelets and study of their roles within the vasculature

Background: Prostaglandins (PGs) and hydroxyeicosatetraeinoic acids (HETEs) are synthesized from arachidonic acid (AA) released from the membrane phospholipids of cells through the activity of cytosolic phospholipase A2α (cPLA2α). In platelets AA is metabolised through cyclooxygenase-1 (COX-1) and 1...

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Bibliographic Details
Main Author: Rauzi, Francesca
Published: Queen Mary, University of London 2015
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.667444