Manipulation of the growth hormone IGF-I axis in type one diabetes : insight into physiological mechanisms and potential strategies for therapeutic intervention

Methods: 1) In a crossover study, 2 doses (5 and 10mg) of a specific GH antagonist (B2036-PEG, Somavert) were each administered for 3 weeks to 7 subjects, in random order with a 3 week washout period. Euglycaemic clamp techniques incorporating cold isotopes were used to quantify carbohydrate and fat...

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Bibliographic Details
Main Author: Williams, Rachel Mair
Published: University of Edinburgh 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.663836