Emergence and expansion of embryonic definitive haematopoietic stem cells

<i>De novo</i> generation and physiological expansion of definitive haematopoietic stem cells (dHSCs) occurs exclusively during embryogenesis and is initiated within the dorsal aorta/para-aortic mesenchyme (Ao) of the E11.5 aorta-gonad-mesonephros (AGM) region. The elucidation of the <...

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Bibliographic Details
Main Author: Taoudi, Samir
Published: University of Edinburgh 2006
Subjects:
611
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.662732