Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels

Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels

The putative CACHD1 gene was identified following a systematic search for ligand-binding proteins as novel drug targets. The CACHD1 gene encodes CACHD1 and has a predicted protein structure similar to that of the [alpha]2[delta] family of voltage-gated Ca2+ channel (VGCC) auxiliary subunits, which m...

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Bibliographic Details
Main Author: Soubrane, Camille Hélène
Published: University of Reading 2014
Subjects:
615.1
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658003
id ndltd-bl.uk-oai-ethos.bl.uk-658003
record_format oai_dc
spelling ndltd-bl.uk-oai-ethos.bl.uk-6580032016-08-04T03:59:33ZIdentification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channelsSoubrane, Camille Hélène2014The putative CACHD1 gene was identified following a systematic search for ligand-binding proteins as novel drug targets. The CACHD1 gene encodes CACHD1 and has a predicted protein structure similar to that of the [alpha]2[delta] family of voltage-gated Ca2+ channel (VGCC) auxiliary subunits, which modulates the biophysical properties and plasma membrane expression of VGCCs. On this basis, the hypothesis that CACHD1 represents a novel [alpha]2[delta]-like VGCC auxiliary subunit was tested.615.1University of Readinghttp://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658003Electronic Thesis or Dissertation
collection NDLTD
sources NDLTD
topic 615.1
spellingShingle 615.1
Soubrane, Camille Hélène
Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels
description The putative CACHD1 gene was identified following a systematic search for ligand-binding proteins as novel drug targets. The CACHD1 gene encodes CACHD1 and has a predicted protein structure similar to that of the [alpha]2[delta] family of voltage-gated Ca2+ channel (VGCC) auxiliary subunits, which modulates the biophysical properties and plasma membrane expression of VGCCs. On this basis, the hypothesis that CACHD1 represents a novel [alpha]2[delta]-like VGCC auxiliary subunit was tested.
author Soubrane, Camille Hélène
author_facet Soubrane, Camille Hélène
author_sort Soubrane, Camille Hélène
title Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels
title_short Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels
title_full Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels
title_fullStr Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels
title_full_unstemmed Identification of CACHD1 as a novel [alpha]2[delta]-like auxiliary subunit of Cav3 voltage-gated calcium channels
title_sort identification of cachd1 as a novel [alpha]2[delta]-like auxiliary subunit of cav3 voltage-gated calcium channels
publisher University of Reading
publishDate 2014
url http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658003
work_keys_str_mv AT soubranecamillehelene identificationofcachd1asanovelalpha2deltalikeauxiliarysubunitofcav3voltagegatedcalciumchannels
_version_ 1718372433989206016

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