Pro-fibrotic effects of all-trans retinoic acid in transforming growth factor-β1-induced fibrogenesis in renal fibroblasts

Retinoids, including the prototypic vitamin A and its main bioactive form, alltrans retinoic acid (tRA), have both anti- and pro-fibrotic effects in renal disease models. To understand and prevent the pro-fibrotic effects of retinoids it is important to establish in vitro models. This work aimed to...

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Bibliographic Details
Main Author: Rankin, Alexandra Catherine
Other Authors: Hendry, Bruce Melville; Xu, Qihe
Published: King's College London (University of London) 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656926