Towards a structural understanding of the mechanism of action of dimeric HCV inhibitors

Hepatitis C Virus (HCV) is expected to be an increasing global healthcare burden. HCV Infection can progress to major chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). No protective vaccine currently exists against hepatitis C and current therapies are ineffective. NS5A is an es...

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Bibliographic Details
Main Author: Lambert, Sebastian Mark
Other Authors: Matthews, Stephen
Published: Imperial College London 2013
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656403