Synthesis of novel Riluzole analogues

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that is universally fatal. The only drug that is currently FDA approved for the treatment of ALS is Riluzole (Figure 1), which improves life expectancy by a few months via an unknown mechanism. This thesis describes the prepar...

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Bibliographic Details
Main Author: Powell, Lucy Alice
Other Authors: Sweeney, Joe
Published: University of Huddersfield 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656299