The expression of alternative splice variants of human epidermal growth factor receptor 2 in invasive breast cancer and cell line models
The Human Epidermal Growth Factor Receptor 2 (HER2) is an oncogene expressed in 25-30% of invasive breast cancers. The HER2 gene encodes an 185kDa transmembrane protein with tyrosine kinase activity. Gene amplification or protein expression of HER2 is a predictor of poor prognosis in women with brea...
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University of the West of England, Bristol
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.655633 |