An integrated approach to the discovery of inhibitors of protein-protein interactions
Protein-protein interactions present challenging targets for therapeutic intervention with enormous potential for modulating biological pathways, particularly in the field of oncology. Two α-helix mediated protein-protein interactions of interest, hypoxia inducible factor-1α (HIF-1α)/p300 and eukary...
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University of Leeds
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.655279 |