Pharmacological strategies to reduce ischemia/reperfusion injury in kidney transplantation

I investigated the influence of the phosphatidylinositol 3-kinase (PI3K)Akt pathway on HSF1 activation status. Despite effecting significant up-regulation of the PI3k/Akt pathway with insulin and insulin-like growth factor-1 (IGF-1), I did not demonstrate any change in the HSF1 trimerisation state,...

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Bibliographic Details
Main Author: Harrison, Ewen M.
Published: University of Edinburgh 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.652166