The synthesis and study of chemically modified anti-HIV antisense oligonucleotides
It has been reported that the presence of a hydrophobic moiety at the 5-position of 2'-deoxyuridine increases duplex stability when incorporated into an oligonucleotide. A series of 2'-deoxyuridine analogues modified at the 5-position have been synthesised. The stability of a 12mer duplex...
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University of Edinburgh
1996
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.651701 |