Role of thymidine kinase 1 phosphorylation on 3'-deoxy-3'-[18F]-fluorothymidine uptake by cancer cells : implication for Positron Emission Tomography
Uncontrolled cell proliferation is one of the hallmarks of cancer and its inhibition is desired in cancer therapy. The thymidine analogue 3'-deoxy-3'-[18F]-fluorothymidine ([18F]FLT) is used to image tumour proliferation by positron emission tomography (PET). To be retained in cells, [18F]...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.650623 |