Effects of methotrexate on human bone cell responses to mechanical stimulation

Mechanical forces influence human bone cell (HBC) metabolism and function. It has been shown that 0.33 Hz cyclical mechanical stimulation results in membrane hyperpolarisation of HBC. Membrane hyperpolarisation follows activation of a mechanotransduction pathway which involves the α<sub>5</...

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Bibliographic Details
Main Author: Elliot, Kerry Jane
Published: University of Edinburgh 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.649984