The impact of target site alterations to fluoroquinolones in Streptococcus pneumoniae

Thirty-one clinical pneumococcal isolates that exhibited decreased sensitivity to the fluoroquinolones were found to express a combination of resistance mechanisms. Efflux inhibition studies have shown that all the selected pneumococcal isolates demonstrated a reduction to ciprofloxacin and norfloxa...

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Bibliographic Details
Main Author: Dorai-Schneiders, Thamarai
Published: University of Edinburgh 2001
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.649652