Glutathione, the redox sensitive transcription factors AP-1 and NF-κB, and early one adenoviral protein in human lung in smoking related lung disease
NF-κB and AP-1 are both redox sensitive transcription factors, and are involved in the regulation of the gene transcription of many pro-inflammatory mediators. AP-1 and NF-κB have a close relationship with γ-glutamylcysteine synthetase (γ-GCS), the rate limiting enzyme in the synthesis of glutathio...
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University of Edinburgh
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648971 |