Involvement of short RNAs in polycomb-mediated gene repression

Involvement of short RNAs in polycomb-mediated gene repression

Polycomb group proteins maintain cell identity by repressing developmental regulator genes specific for other cell types. There are two main complexes: Polycomb repressive complex 1 (PRC1) and 2 (PRC2). PRC2 methylates histone H3 lysine 27 (H3K27me3), creating a binding site for PRC1 that ubiquitina...

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Bibliographic Details
Main Author:	Araújo, C. C.
Published:	University College London (University of London) 2015
Subjects:	616
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.647269

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