In vitro analysis of C-terminal mutations of the murine PrP gene

PrP undergoes three major post-translational changes, N-terminal cleavage, N-linked glycosylation and the cleavage of a C-terminal peptide with the subsequent addition of a phosphatidylinositolglycolpipid (GPI-anchor), which is responsible for the protein's attachment to the membrane (ref, Stah...

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Bibliographic Details
Main Author: Coleman, Michele
Published: University of Edinburgh 1994
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.643325