An investigation into the role of Rab-Coupling Protein and EphA2 during cancer cell migration

The gene encoding Rab-Coupling Protein (RCP), a Rab11 GTPase effector, is found on a chromosomal locus that is frequently amplified in cancer. We have previously shown that RCP drives alpha5beta1-integrin and EGFR recycling to the plasma membrane, thus contributing to the invasive migration of tumou...

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Bibliographic Details
Main Author: Gundry, Christine
Published: University of Glasgow 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.643110