Chemo-enzymatic approaches to morphine-6-glucuronide and selected analogues
Morphine 1 is metabolised in the liver into its active form, morphine-6-glucuronide (M6G) 2. When M6G 2 is administered directly to patients it has greater analgesic potency than morphine 1 and this stimulated interest in the synthesis of M6G 2 as a novel analgesic. We have examined several syntheti...
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University of Edinburgh
1998
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641879 |