Expanded CTG trinucleotide repeats stimulate homologous recombination in Escherichia coli

Expanded trinucleotide repeats (TNRs) (e.g. CAG, CTG, CCG) cause 40 different human diseases, however the molecular mechanism underlying the expansion of TNRs is poorly understood. This work describes the integration, in the chromosome of the bacterium <i>Escherichia coli</i> of differen...

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Bibliographic Details
Main Author: Blackwood, John Kenneth
Published: University of Edinburgh 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641694