Functional analysis of ICAD-S protein and the development of a novel technology for site-specific protein cleavage in vertebrate cells
CAD (Caspase Activated DNase) exists in a complex with its inhibitor ICAD in intact cells. To study the particular role of ICAD splice forms ICAD-S and ICAD-L <i>in vivo</i> I constructed DT40 cell lines in which the ICAD or ICAD plus CAD ORFs had been deleted. ICAD and ICAD/CAD double k...
| Main Author: | |
|---|---|
| Published: |
University of Edinburgh
2007
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640224 |