Bridging the obesity gap : a role for connexin and pannexin signalling in adipogenesis

Obesity is currently a worldwide health problem associated with conditions such as type 2 diabetes. It has been reported that connexins may be involved in adipogenesis but the underlying mechanism remains unresolved. Adipose tissue from male Zucker fatty rats (falfa), male lean rats (fa-I-) and 3T3-...

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Bibliographic Details
Main Author: Ofori-Frimpong, Boatemaa
Published: Glasgow Caledonian University 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636817
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Summary:Obesity is currently a worldwide health problem associated with conditions such as type 2 diabetes. It has been reported that connexins may be involved in adipogenesis but the underlying mechanism remains unresolved. Adipose tissue from male Zucker fatty rats (falfa), male lean rats (fa-I-) and 3T3-Ll cells were investigated for connexin (Cx) and pannexin expression profiles, Cx localization and function and lipid accumulation during the differentiation programme.