Apoptosis regulation at mitochondria : insights into the roles of CKMT1 and IkBα in apoptosis inhibition
The point of no return in the intrinsic apoptosis pathway is the loss of outer mitochondrial membrane integrity. Protein complexes, such as the PT-pore, have been implicated in mediating mitochondrial disintegration via the induction of mitochondrial permeability transition (MPT). My study provides...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634076 |