Mechanisms of colorectal tumorigenesis associated with Mut-Y (MYH) deficiency and identification of novel predisposition genes in the multiple adenoma phenotype

The main subjects of my thesis can be divided into three related areas. Firstly, determination of the mechanisms of tumoriogenesis associated with a recently identified, recessively inherited syndrome, AfrTZ-associated polyposis (MAP). MAP results from defective base excision repair (BER) caused by...

Full description

Bibliographic Details
Main Author: Thirlwell, C.
Published: University College London (University of London) 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631754