The role of Jagged1 as a pivotal regulator of neural stem cell differentiation in the neurogenic niche
During formation of the brain in mammals, neural stem cells (NSCs) transit through sequential periods of expansion, neurogenesis and gliogenesis. Notch signaling maintains NSCs and blocks transcription of pro-neurogenic factors. Notch ligands are expressed by differentiating progenitors and activate...
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University of Sheffield
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631432 |