The role of the P2Y12 receptor in the vessel wall response to injury and inflammation

Platelets play a fundamental role in thrombosis, but they are increasingly regarded as discrete immune cells due to their pro-inflammatory actions on leukocytes and the endothelium. The P2Y12 receptor is responsible for amplifying and sustaining platelet activation. As a result, P2Y12 inhibitors, su...

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Bibliographic Details
Main Author: West, Laura Elizabeth
Other Authors: Storey, Robert F. ; Francis, Sheila E.
Published: University of Sheffield 2014
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631423