Investigating the role of P2Y12 in thrombosis, inflammation and infection in the zebrafish model
The P2Y12 receptor is an important amplifier of thrombosis. P2Y12 is activated by ADP, inducing release of a and dense granules from the platelet. a-granules contain a myriad of proteins including pro-inflammatory mediators involved in vascular inflammation. P2Y12 antagonists are used in the treatme...
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University of Sheffield
2014
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631422 |