Evaluation of targeted methylation at the CDKN2B promoter

DNA 5- Cytosine methylation is a modification that occurs in mammalian cells predominantly at CpG sequences, through addition of a methyl group to the C5 position of cytosine. It is a commonly held view in the current field of epigenetics that the aberrant methylation patterns observed in gene promo...

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Bibliographic Details
Main Author: Lamadema, Nermina
Published: King's College London (University of London) 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631255