Novel cell-penetrating peptide-based vectors for siRNA delivery

Harnessing the RNAi pathway with synthetic siRNA as a potent and selective mode of post-transcriptional gene silencing and has therapeutic potential in personalised medicine; however, the large size and negative charge of siRNA creates a hurdle for intracellular delivery that has thus far limited it...

Full description

Bibliographic Details
Main Author: Tsimon, Myrsini
Published: University of Westminster 2014
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.630494