Antibiotic discovery and development using structural analysis of DNA adenine methyltransferase inhibitors

The requirement for developing antibiotics is continually increasing due to the rise in antibiotic resistance and lack of novel compounds that bypass the known resistance mechanisms. A well-characterised target for such development is DNA adenine methyltransferase (Dam), a suitable candidate because...

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Bibliographic Details
Main Author: Harmer, Jennifer
Other Authors: Roach, Peter
Published: University of Southampton 2014
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628740