Protein engineering and characterization of a stable trimeric form of CD23 and a fluorescent IgE biosensor

Immunoglobulin E (IgE) plays a critical role in allergic diseases such as asthma and atopic dermatitis. Cross-linking of IgE bound to its high affinity receptor, FceRI, by allergen on mast cells and basophils results in the release of inflammatory mediators and induces allergic reactions. IgE can al...

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Bibliographic Details
Main Author: Kao, Wen-Pin
Published: King's College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628300