Targeting therapeutic T cells to tumour niches
CXCR4 and CXCL12 are known to work in concert to mediate cell proliferation, survival and migration. These functions have a bearing on physiological cellular events such as haematopoietic cell recruitment to, and survival within, the bone marrow (BM) compartment. This axis can mediate analogous func...
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University College London (University of London)
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626687 |