Molecular and cellular evaluation of novel DNA sequence selective polyamides
Pyrrole (P)-Imidazole (I) containing polyamides are small synthetic molecules which can target predetermined DNA sequences with high affinity and modulate gene expression by interfering with the binding of transcription factors to DNA. Hairpin and H-pin analogues show enhanced DNA binding affinity a...
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University College London (University of London)
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626330 |