Biochemical and structural characterisation of infectious mammalian prions
The central feature of prion disease is the conversion of normal host‐encoded cellular prion protein to an abnormal isoform; designated PrPSc. Current research has shown that PrPSc is the principal, and possibly the sole, component of infectious prions. Despite a wealth of experimental data that sup...
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University College London (University of London)
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625590 |