Role of the Syk tyrosine kinase in mature B cell function

Signal transduction through the antigen receptor of B cells (BCR) is crucial in controlling their development and maintenance, and is also needed for B cell immune responses. Syk, a protein tyrosine kinase, has already been implicated in signalling downstream of the BCR. Mice deficient for Syk show...

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Bibliographic Details
Main Author: Nys, J.
Published: University College London (University of London) 2010
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625350