Generation of antigen-specific regulatory T cells by T cell receptor gene transfer

Regulatory T cells (Tregs) have shown considerable potential in the treatment of murine models of immuno-pathology. Whilst poly-clonal Tregs are able to suppress immuno-pathology in a number of models, the superiority of Ag-specific Treg treatment has been demonstrated using Tregs from T cell recept...

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Bibliographic Details
Main Author: Wright, G. P.
Published: University College London (University of London) 2009
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625252