Patent foramen ovale, cerebral microembolisation and cognitive function in dialysis
Dialysis in patients with kidney disease is associated with cognitive decline. The reasons for this are multifactorial but in haemodialysis (HD) patients it is postulated that paradoxical embolisation of material from the extracorporeal circuit may occur across a right-to-left shunt, such as a paten...
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University of Brighton
2013
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619025 |
| Summary: | Dialysis in patients with kidney disease is associated with cognitive decline. The reasons for this are multifactorial but in haemodialysis (HD) patients it is postulated that paradoxical embolisation of material from the extracorporeal circuit may occur across a right-to-left shunt, such as a patent foramen ovale (PFO), and cause cerebral damage. We aimed to identify the prevalence of PFO in dialysis patients and to assess for evidence of cerebral microembolisation during HD and continuous veno-venous haemofiltration (CVVH). We also wished to correlate the presence of PFO with rates of cognitive decline. |
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